LSD to Treat Alcoholism

LSD was first found to help sufferers overcome various forms of addiction back in the 1960s, at the height of the first wave of psychedelic research. A fifty-year hiatus on this field of scientific investigation then followed, before finally ending with the spectacular findings of the world’s first LSD brain imaging study. The results of this research revealed how the drug shuts off the a brain region called the default mode network (DMN), which controls and restricts consciousness and is strongly associated with rigid modes of thought and cognition, such as those underlying addiction.

In light of this discovery, we are now preparing a research project in collaboration with Dr Michael Bogenschutz and the University of New Mexico, looking into the efficacy of LSD as a treatment for alcoholism. This double-blind, placebo-controlled study will seek to reveal whether LSD reduces cravings and drinking during the week following its administration.

The study authors will also use fMRI to observe how taking LSD alters activity in the brain regions that are associated with craving and addiction, such as the medial prefrontal, ventromedial prefrontal, orbitofrontal, and posterior cingulate cortices.

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